CLNICAL TRIALS WARSZAW

Psoriatic Arthritis (PsA)

Psoriasis is not just a skin disease. Up to 20% of psoriasis patients also suffer from psoriatic arthritis.

Symptoms of the Disease
The disease can take a different course in different patients. Most often, several joints are involved asymmetrically, e.g., the knee, ankle, or elbow. Individual distal joints of the fingers or toes may also be affected (the characteristic “sausage digit” or “radish-like” appearance). Sometimes the inflammatory process involves the joints of the hands and feet symmetrically, and the disease requires differentiation from rheumatoid arthritis (RA). Usually, the rheumatoid factor characteristic of RA is not found in the serum.

In some patients, psoriatic arthritis resembles the course of ankylosing spondylitis, presenting with inflammatory pain in the spine and sacroiliac joints.

Treatment of Psoriatic Arthritis

A rheumatologist typically begins therapy with classic disease-modifying antirheumatic drugs (DMARDs), which include: Methotrexate, Sulfasalazine, or Leflunomide.

Treatment is determined individually for each patient, depending on the activity and course of PsA. If therapy with classic drugs proves ineffective, patients are qualified for biologic therapy.

Goals of PsA treatment:

  • Reduction or resolution of pain, stiffness, and swelling.
  • Improvement of function in the affected joints.
  • Enhancement of quality of life.
  • Inhibition of disease progression and prevention of disability.
  • Furthermore, drugs used in the treatment of PsA reduce or eliminate skin lesions.

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Psoriatic Arthritis (PsA)

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